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Digital PCR

The identification of predefined mutations expected to be present in a minor fraction of a cell population is important for a variety of basic research and clinical applications. Here, we describe an approach for transforming the exponential, analog nature of the PCR into a linear, digital signal su...

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Autors principals: Vogelstein, Bert, Kinzler, Kenneth W.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC17763/
https://ncbi.nlm.nih.gov/pubmed/10430926
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