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Targeting kinases with precision
Cancer genomics and mechanistic studies have revealed that heterogeneous mutations within a single kinase can result in a variety of activation mechanisms. The challenge has been to match these insights with tailored drug discovery strategies to yield potent, highly selective drugs. With optimized d...
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| 出版年: | Mol Cell Oncol |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6149809/ https://ncbi.nlm.nih.gov/pubmed/30250891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1435183 |
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