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Rational targeting of BRAF and PI3-Kinase signaling for melanoma therapy
Although mitogen-activated protein kinase (MAPK) inhibitors elicit initial regression of BRAF-mutated melanoma, drug resistance is an inevitable and fatal event. We recently reported that in genetically engineered mouse models of BRAF-mutated melanoma, isoform-selective phosphatidylinositol 3-kinase...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4909456/ https://ncbi.nlm.nih.gov/pubmed/27314067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1033095 |
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