BRAF-targeted therapy and immune responses to melanoma

Type I BRAF inhibitors and immunotherapy constitute two new exciting approaches for the treatment of advanced malignant melanoma. We have recently elucidated a role for host C-C chemokine receptor type 2 (CCR2) in the antineoplastic effects of type I BRAF inhibitors in mice, supporting the therapeut...

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Main Authors: Ngiow, Shin Foong, Knight, Deborah A, Ribas, Antoni, McArthur, Grant A, Smyth, Mark J.
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716742/
https://ncbi.nlm.nih.gov/pubmed/23894707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24462
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