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Natural Killer cell control of BRAF(V600E) mutant melanoma during targeted therapy

Pharmacologic inhibition of the mutant BRAF(V600E) protein in advanced BRAF(V600E) melanoma results in a high proportion of patients that respond, but few with durable responses. We have recently revealed that Natural Killer (NK) cells play an essential role in the BRAF(V600E) inhibitor control of m...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: de Andrade, Lucas Ferrari, Ngiow, Shin Foong, Martinet, Ludovic, Smyth, Mark J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485837/
https://ncbi.nlm.nih.gov/pubmed/26137412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.998119
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