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Natural Killer cell control of BRAF(V600E) mutant melanoma during targeted therapy

Pharmacologic inhibition of the mutant BRAF(V600E) protein in advanced BRAF(V600E) melanoma results in a high proportion of patients that respond, but few with durable responses. We have recently revealed that Natural Killer (NK) cells play an essential role in the BRAF(V600E) inhibitor control of m...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: de Andrade, Lucas Ferrari, Ngiow, Shin Foong, Martinet, Ludovic, Smyth, Mark J
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485837/
https://ncbi.nlm.nih.gov/pubmed/26137412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2014.998119
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