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Targeting RAF kinases for cancer therapy: BRAF mutated melanoma and beyond
The identification of mutationally activated BRAF in many cancers altered our conception of the role played by the RAF family of protein kinases in oncogenesis. In this review we describe the development of BRAF inhibitors and the results that have emerged from their analysis in both the laboratory...
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| Foilsithe in: | Nat Rev Cancer |
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| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250230/ https://ncbi.nlm.nih.gov/pubmed/24957944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3760 |
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