Llwytho...

Rational targeting of BRAF and PI3-Kinase signaling for melanoma therapy

Although mitogen-activated protein kinase (MAPK) inhibitors elicit initial regression of BRAF-mutated melanoma, drug resistance is an inevitable and fatal event. We recently reported that in genetically engineered mouse models of BRAF-mutated melanoma, isoform-selective phosphatidylinositol 3-kinase...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Oncol
Prif Awduron: Deuker, Marian M., McMahon, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4909456/
https://ncbi.nlm.nih.gov/pubmed/27314067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1033095
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