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Targeting kinases with precision
Cancer genomics and mechanistic studies have revealed that heterogeneous mutations within a single kinase can result in a variety of activation mechanisms. The challenge has been to match these insights with tailored drug discovery strategies to yield potent, highly selective drugs. With optimized d...
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| Pubblicato in: | Mol Cell Oncol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6149809/ https://ncbi.nlm.nih.gov/pubmed/30250891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1435183 |
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