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Contribution of Polycomb Homologues Bmi-1 and Mel-18 to Medulloblastoma Pathogenesis

Bmi-1 and Mel-18 are structural homologues that belong to the Polycomb group of transcriptional regulators and are believed to stably maintain repression of gene expression by altering the state of chromatin at specific promoters. While a number of clinical and experimental observations have implica...

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Detalhes bibliográficos
Main Authors: Wiederschain, Dmitri, Chen, Lin, Johnson, Brett, Bettano, Kimberly, Jackson, Dowdy, Taraszka, John, Wang, Y. Karen, Jones, Michael D., Morrissey, Michael, Deeds, James, Mosher, Rebecca, Fordjour, Paul, Lengauer, Christoph, Benson, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951487/
https://ncbi.nlm.nih.gov/pubmed/17452456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02244-06
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