Contribution of Polycomb Homologues Bmi-1 and Mel-18 to Medulloblastoma Pathogenesis

Bmi-1 and Mel-18 are structural homologues that belong to the Polycomb group of transcriptional regulators and are believed to stably maintain repression of gene expression by altering the state of chromatin at specific promoters. While a number of clinical and experimental observations have implica...

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Hauptverfasser: Wiederschain, Dmitri, Chen, Lin, Johnson, Brett, Bettano, Kimberly, Jackson, Dowdy, Taraszka, John, Wang, Y. Karen, Jones, Michael D., Morrissey, Michael, Deeds, James, Mosher, Rebecca, Fordjour, Paul, Lengauer, Christoph, Benson, John D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951487/
https://ncbi.nlm.nih.gov/pubmed/17452456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02244-06
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