Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion

BACKGROUND: Medulloblastoma is the most common intracranial childhood malignancy and a genetically heterogeneous disease. Despite recent advances, current therapeutic approaches are still associated with high morbidity and mortality. Recent molecular profiling has suggested the stratification of med...

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Detalhes bibliográficos
Main Authors: Merve, Ashirwad, Dubuc, Adrian M, Zhang, Xinyu, Remke, Marc, Baxter, Patricia A, Li, Xiao-Nan, Taylor, Michael D, Marino, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928978/
https://ncbi.nlm.nih.gov/pubmed/24460684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-10
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