PI3Kα Inhibitors That Inhibit Metastasis

Previous genetic analyses have suggested that mutations of the genes encoding PI3Kα facilitate invasion and metastasis but have less effect on primary tumor growth. These findings have major implications for therapeutics but have not been factored into pre-clinical drug development designs. Here we...

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Bibliografski detalji
Glavni autori: Schmidt-Kittler, Oleg, Zhu, Jiuxiang, Yang, Jian, Liu, Guosheng, Hendricks, William, Lengauer, Christoph, Gabelli, Sandra B., Kinzler, Kenneth W., Vogelstein, Bert, Huso, David L., Zhou, Shibin
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2010
Teme:
Research Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004370/
https://ncbi.nlm.nih.gov/pubmed/21179398
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