ロード中...
Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design
PIK3CA , the gene that encodes the catalytic subunit of phosphatidylinositol 3-kinase α (PI3Kα), is frequently mutated in breast and other types of cancer. A specific inhibitor that targets the mutant forms of PI3Kα could maximize treatment efficiency while minimizing side-effects. Herein we describ...
保存先:
| 出版年: | Bioorg Med Chem |
|---|---|
| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5319926/ https://ncbi.nlm.nih.gov/pubmed/28129991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.01.012 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|