TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer

BACKGROUND: Muscle-invasive bladder cancer (MIBC) is an aggressive neoplasm with poor prognosis, lacking effective therapeutic targets. Oncogenic dependency on members of the TAM tyrosine kinase receptor family (TYRO3, AXL, MERTK) has been reported in several cancer types, but their role in bladder...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Dufour, Florent, Silina, Linda, Neyret-Kahn, Hélène, Moreno-Vega, Aura, Krucker, Clémentine, Karboul, Narjesse, Dorland-Galliot, Marion, Maillé, Pascale, Chapeaublanc, Elodie, Allory, Yves, Stransky, Nicolas, Haegel, Hélène, Menguy, Thierry, Duong, Vanessa, Radvanyi, François, Bernard-Pierrot, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461973/
https://ncbi.nlm.nih.gov/pubmed/30765874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0397-6
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