TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer

BACKGROUND: Muscle-invasive bladder cancer (MIBC) is an aggressive neoplasm with poor prognosis, lacking effective therapeutic targets. Oncogenic dependency on members of the TAM tyrosine kinase receptor family (TYRO3, AXL, MERTK) has been reported in several cancer types, but their role in bladder...

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Udgivet i:Br J Cancer
Main Authors: Dufour, Florent, Silina, Linda, Neyret-Kahn, Hélène, Moreno-Vega, Aura, Krucker, Clémentine, Karboul, Narjesse, Dorland-Galliot, Marion, Maillé, Pascale, Chapeaublanc, Elodie, Allory, Yves, Stransky, Nicolas, Haegel, Hélène, Menguy, Thierry, Duong, Vanessa, Radvanyi, François, Bernard-Pierrot, Isabelle
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461973/
https://ncbi.nlm.nih.gov/pubmed/30765874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0397-6
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