Measurement of enzyme kinetics and inhibitor constants using enthalpy arrays

Tekijä Recht, Michael I., Torres, Frank E., De Bruyker, Dirk, Bell, Alan G., Klumpp, Martin, Bruce, Richard H.
Julkaistu 2009

Development and validation of a generic fluorescent methyltransferase activity assay based on the Transcreener(®) AMP/GMP Assay

Tekijä Klink, Tony A., Staeben, Matt, Twesten, Kim, Kopp, Andrew L., Kumar, Meera, Dunn, Rebecca Schall, Pinchard, Cori A., Kleman-Leyer, Karen M., Klumpp, Martin, Lowery, Robert G.
Julkaistu 2011

Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach

Tekijä Chen, Chao, Zhu, Hugh, Stauffer, Frédéric, Caravatti, Giorgio, Vollmer, Susanne, Machauer, Rainer, Holzer, Philipp, Möbitz, Henrik, Scheufler, Clemens, Klumpp, Martin, Tiedt, Ralph, Beyer, Kim S., Calkins, Keith, Guthy, Daniel, Kiffe, Michael, Zhang, Jeff, Gaul, Christoph
Julkaisussa ACS Med Chem Lett (2016)

PIKfyve, a class III PI-kinase, is the target of the small molecular IL12/23 inhibitor apilimod and a new player in toll-like receptor signaling

Tekijä Cai, Xinming, Xu, Yongyao, Cheung, Atwood K., Tomlinson, Ronald C., Alcázar-Román, Abel, Murphy, Leon, Billich, Andreas, Zhang, Bailin, Feng, Yan, Klumpp, Martin, Rondeau, Jean-Michel, Fazal, Aleem N., Wilson, Christopher J., Myer, Vic, Joberty, Gerard, Bouwmeester, Tewis, Labow, Mark A., Finan, Peter M., Porter, Jeffrey A., Ploegh, Hidde L., Baird, Daniel, De Camilli, Pietro, Tallarico, John A., Huang, Qian
Julkaisussa Chem Biol (2013)