Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo

Por Honda, Ayako, Harrington, Edmund, Cornella-Taracido, Ivan, Furet, Pascal, Knapp, Mark S., Glick, Meir, Triantafellow, Ellen, Dowdle, William E., Wiedershain, Dmitri, Maniara, Wieslawa, Moore, Christine, Finan, Peter M., Hamann, Lawrence G., Firestone, Brant, Murphy, Leon O., Keaney, Erin P.
Publicado no ACS Med Chem Lett (2015)

Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism

Por Bilanges, Benoit, Alliouachene, Samira, Pearce, Wayne, Morelli, Daniele, Szabadkai, Gyorgy, Chung, Yuen-Li, Chicanne, Gaëtan, Valet, Colin, Hill, Julia M., Voshol, Peter J., Collinson, Lucy, Peddie, Christopher, Ali, Khaled, Ghazaly, Essam, Rajeeve, Vinothini, Trichas, Georgios, Srinivas, Shankar, Chaussade, Claire, Salamon, Rachel S., Backer, Jonathan M., Scudamore, Cheryl L., Whitehead, Maria A., Keaney, Erin P., Murphy, Leon O., Semple, Robert K., Payrastre, Bernard, Tooze, Sharon A., Vanhaesebroeck, Bart
Publicado no Nat Commun (2017)