X-ray crystal structure of ornithine acetyltransferase from the clavulanic acid biosynthesis gene cluster

Por Elkins, Jonathan M., Kershaw, Nadia J., Schofield, Christopher J.
Publicado em 2005

Fragment screening of cyclin G-associated kinase by weak affinity chromatography

Por Meiby, Elinor, Knapp, Stefan, Elkins, Jonathan M., Ohlson, Sten
Publicado em 2012

Crystal Structure of Human Aurora B in Complex with INCENP and VX-680

Por Elkins, Jonathan M., Santaguida, Stefano, Musacchio, Andrea, Knapp, Stefan
Publicado em 2012

The centaurin γ-1 GTPase-like domain functions as an NTPase

Por Soundararajan, Meera, Yang, Xiaowen, Elkins, Jonathan M., Sobott, Frank, Doyle, Declan A.
Publicado em 2007

Analysis of conditions affecting auto-phosphorylation of human kinases during expression in bacteria

Por Shrestha, Amit, Hamilton, Garth, O’Neill, Eric, Knapp, Stefan, Elkins, Jonathan M.
Publicado em 2012

Crystal Structure of Sphingosine Kinase 1 with PF-543

Por Wang, Jing, Knapp, Stefan, Pyne, Nigel J., Pyne, Susan, Elkins, Jonathan M.
Publicado no ACS Med Chem Lett (2014)

Structure of dystrophia myotonica protein kinase

Por Elkins, Jonathan M, Amos, Ann, Niesen, Frank H, Pike, Ashley CW, Fedorov, Oleg, Knapp, Stefan
Publicado em 2009

Crystal Structures of ABL-Related Gene (ABL2) in Complex with Imatinib, Tozasertib (VX-680), and a Type I Inhibitor of the Triazole Carbothioamide Class

Por Salah, Eidarus, Ugochukwu, Emilie, Barr, Alastair J., von Delft, Frank, Knapp, Stefan, Elkins, Jonathan M.
Publicado em 2011

Structural insights into the activation of MST3 by MO25

Por Mehellou, Youcef, Alessi, Dario R., Macartney, Thomas J., Szklarz, Marta, Knapp, Stefan, Elkins, Jonathan M.
Publicado em 2013

The crystal structure of the RhoA–AKAP-Lbc DH–PH domain complex

Por Abdul Azeez, Kamal R., Knapp, Stefan, Fernandes, João M. P., Klussmann, Enno, Elkins, Jonathan M.
Publicado no Biochem J (2014)

Identification and Structure–Function Analysis of Subfamily Selective G Protein-Coupled Receptor Kinase Inhibitors

Por Homan, Kristoff T., Larimore, Kelly M., Elkins, Jonathan M., Szklarz, Marta, Knapp, Stefan, Tesmer, John J. G.
Publicado no ACS Chem Biol (2014)

Structures of the CDK12/CycK complex with AMP-PNP reveal a flexible C-terminal kinase extension important for ATP binding

Por Dixon-Clarke, Sarah E., Elkins, Jonathan M., Cheng, S.-W. Grace, Morin, Gregg B., Bullock, Alex N.
Publicado no Sci Rep (2015)

Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions

Por Elkins, Jonathan M., Papagrigoriou, Evangelos, Berridge, Georgina, Yang, Xiaowen, Phillips, Claire, Gileadi, Carina, Savitsky, Pavel, Doyle, Declan A.
Publicado em 2007

Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms

Por Elkins, Jonathan M, Gileadi, Carina, Shrestha, Leela, Phillips, Claire, Wang, Jing, Muniz, João R C, Doyle, Declan A
Publicado em 2010

Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis.

Por Elkins, Jonathan M, Clifton, Ian J, Hernández, Helena, Doan, Linh X, Robinson, Carol V, Schofield, Christopher J, Hewitson, Kirsty S
Publicado em 2002

Structural basis for protein–protein interactions in the 14-3-3 protein family

Por Yang, Xiaowen, Lee, Wen Hwa, Sobott, Frank, Papagrigoriou, Evangelos, Robinson, Carol V., Grossmann, J. Günter, Sundström, Michael, Doyle, Declan A., Elkins, Jonathan M.
Publicado em 2006

Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition

Por Soundararajan, Meera, Roos, Annette K., Savitsky, Pavel, Filippakopoulos, Panagis, Kettenbach, Arminja N., Olsen, Jesper V., Gerber, Scott A., Eswaran, Jeyanthy, Knapp, Stefan, Elkins, Jonathan M.
Publicado em 2013

X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor

Por Elkins, Jonathan M., Wang, Jing, Deng, Xianming, Pattison, Michael J., Arthur, J. Simon C., Erazo, Tatiana, Gomez, Nestor, Lizcano, Jose M., Gray, Nathanael S., Knapp, Stefan
Publicado em 2013

Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones

Por Deng, Xianming, Elkins, Jonathan M., Zhang, Jinwei, Yang, Qingkai, Erazo, Tatiana, Gomez, Nestor, Choi, Hwan Geun, Wang, Jinhua, Dzamko, Nicolas, Lee, Jiing-Dwan, Sim, Taebo, Kim, NamDoo, Alessi, Dario R., Lizcano, Jose M., Knapp, Stefan, Gray, Nathanael S.
Publicado em 2013

Stereospecific targeting of MTH1 by (S)-crizotinib as anticancer strategy

Por Huber, Kilian V. M., Salah, Eidarus, Radic, Branka, Gridling, Manuela, Elkins, Jonathan M., Stukalov, Alexey, Jemth, Ann-Sofie, Gokturk, Camilla, Sanjiv, Kumar, Strömberg, Kia, Pham, Therese, Berglund, Ulrika Warpman, Colinge, Jacques, Bennett, Keiryn L., Loizou, Joanna, Helleday, Thomas, Knapp, Stefan, Superti-Furga, Giulio
Publicado em 2014