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Structure of dystrophia myotonica protein kinase

Dystrophia myotonica protein kinase (DMPK) is a serine/threonine kinase composed of a kinase domain and a coiled-coil domain involved in the multimerization. The crystal structure of the kinase domain of DMPK bound to the inhibitor bisindolylmaleimide VIII (BIM-8) revealed a dimeric enzyme associate...

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Autors principals: Elkins, Jonathan M, Amos, Ann, Niesen, Frank H, Pike, Ashley CW, Fedorov, Oleg, Knapp, Stefan
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762590/
https://ncbi.nlm.nih.gov/pubmed/19309729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.82
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