Cell biology: A key driver of therapeutic innovation

door Hantschel, Oliver, Superti-Furga, Giulio
Gepubliceerd in 2012

SLC38A9: A lysosomal amino acid transporter at the core of the amino acid-sensing machinery that controls MTORC1

door Rebsamen, Manuele, Superti-Furga, Giulio
Gepubliceerd in Autophagy (2015)

Targeting allosteric regulatory modules in oncoproteins: “Drugging the Undruggable”

door Hantschel, Oliver, Grebien, Florian, Superti-Furga, Giulio
Gepubliceerd in 2011

The Growing Arsenal of ATP-Competitive and Allosteric Inhibitors of BCR–ABL

door Hantschel, Oliver, Grebien, Florian, Superti-Furga, Giulio
Gepubliceerd in 2012

Recent advances in combinatorial drug screening and synergy scoring

door Pemovska, Tea, Bigenzahn, Johannes W, Superti-Furga, Giulio
Gepubliceerd in Curr Opin Pharmacol (2018)

A guide to plasma membrane solute carrier proteins

door Pizzagalli, Mattia D., Bensimon, Ariel, Superti‐Furga, Giulio
Gepubliceerd in FEBS J (2020)

IFITs: Emerging Roles as Key Anti-Viral Proteins

door Vladimer, Gregory I., Górna, Maria W., Superti-Furga, Giulio
Gepubliceerd in 2014

Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A

door Gorelik, Alexei, Illes, Katalin, Superti-Furga, Giulio, Nagar, Bhushan
Gepubliceerd in J Biol Chem (2016)

Detection of Chemical Engagement of Solute Carrier Proteins by a Cellular Thermal Shift Assay

door Hashimoto, Mari, Girardi, Enrico, Eichner, Ruth, Superti-Furga, Giulio
Gepubliceerd in ACS Chem Biol (2018)

The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)

door Winger, Jonathan A, Hantschel, Oliver, Superti-Furga, Giulio, Kuriyan, John
Gepubliceerd in 2009

Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity

door Lorenz, Sonja, Deng, Patricia, Hantschel, Oliver, Superti-Furga, Giulio, Kuriyan, John
Gepubliceerd in Biochem J (2015)

Crystal structure of mammalian acid sphingomyelinase

door Gorelik, Alexei, Illes, Katalin, Heinz, Leonhard X., Superti-Furga, Giulio, Nagar, Bhushan
Gepubliceerd in Nat Commun (2016)

Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity

door Gorelik, Alexei, Heinz, Leonhard X., Illes, Katalin, Superti-Furga, Giulio, Nagar, Bhushan
Gepubliceerd in J Biol Chem (2016)

c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis

door Furstoss, Olivia, Dorey, Karel, Simon, Valérie, Barilà, Daniela, Superti-Furga, Giulio, Roche, Serge
Gepubliceerd in 2002

A Computational Approach to Analyze the Mechanism of Action of the Kinase Inhibitor Bafetinib

door Burkard, Thomas R., Rix, Uwe, Breitwieser, Florian P., Superti-Furga, Giulio, Colinge, Jacques
Gepubliceerd in 2010

Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins

door Abbas, Yazan M., Pichlmair, Andreas, Górna, Maria W., Superti-Furga, Giulio, Nagar, Bhushan
Gepubliceerd in Nature (2013)

NSs Protein of Sandfly Fever Sicilian Phlebovirus Counteracts Interferon (IFN) Induction by Masking the DNA-Binding Domain of IFN Regulatory Factor 3

door Wuerth, Jennifer Deborah, Habjan, Matthias, Wulle, Julia, Superti-Furga, Giulio, Pichlmair, Andreas, Weber, Friedemann
Gepubliceerd in J Virol (2018)

Caspase-Dependent Cleavage of c-Abl Contributes to Apoptosis

door Barilà, Daniela, Rufini, Alessandra, Condò, Ivano, Ventura, Natascia, Dorey, Karel, Superti-Furga, Giulio, Testi, Roberto
Gepubliceerd in 2003

A nuclear tyrosine phosphorylation circuit: c-Jun as an activator and substrate of c-Abl and JNK

door Barilá, Daniela, Mangano, Raffaella, Gonfloni, Stefania, Kretzschmar, Jana, Moro, Marina, Bohmann, Dirk, Superti-Furga, Giulio
Gepubliceerd in 2000

Building and exploring an integrated human kinase network: Global organization and medical entry points()

door Colinge, Jacques, César-Razquin, Adrián, Huber, Kilian, Breitwieser, Florian P., Májek, Peter, Superti-Furga, Giulio
Gepubliceerd in 2014