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Caspase-Dependent Cleavage of c-Abl Contributes to Apoptosis

The nonreceptor tyrosine kinase c-Abl may contribute to the regulation of apoptosis. c-Abl activity is induced in the nucleus upon DNA damage, and its activation is required for execution of the apoptotic program. Recently, activation of nuclear c-Abl during death receptor-induced apoptosis has been...

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Publicado no:Mol Cell Biol
Principais autores: Barilà, Daniela, Rufini, Alessandra, Condò, Ivano, Ventura, Natascia, Dorey, Karel, Superti-Furga, Giulio, Testi, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2003
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152541/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12665579/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.8.2790-2799.2003
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