Caspase-Dependent Cleavage of c-Abl Contributes to Apoptosis

The nonreceptor tyrosine kinase c-Abl may contribute to the regulation of apoptosis. c-Abl activity is induced in the nucleus upon DNA damage, and its activation is required for execution of the apoptotic program. Recently, activation of nuclear c-Abl during death receptor-induced apoptosis has been...

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Bibliographic Details
Main Authors: Barilà, Daniela, Rufini, Alessandra, Condò, Ivano, Ventura, Natascia, Dorey, Karel, Superti-Furga, Giulio, Testi, Roberto
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC152541/
https://ncbi.nlm.nih.gov/pubmed/12665579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.8.2790-2799.2003
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