c-Src-Mediated Phosphorylation of hnRNP K Drives Translational Activation of Specifically Silenced mRNAs

hnRNPK and hnRNP E1/E2 mediate translational silencing of cellular and viral mRNAs in a differentiation-dependent way by binding to specific regulatory sequences. The translation of 15-lipoxygenase (LOX) mRNA in erythroid precursor cells and of the L2 mRNA of human papilloma virus type 16 (HPV-16) i...

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Autori principali: Ostareck-Lederer, Antje, Ostareck, Dirk H., Cans, Christophe, Neubauer, Gitte, Bomsztyk, Karol, Superti-Furga, Giulio, Hentze, Matthias W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC133888/
https://ncbi.nlm.nih.gov/pubmed/12052863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4535-4543.2002
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