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c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis

The mechanism by which the ubiquitously expressed Src family kinases regulate mitogenesis is not well understood. Here we report that cytoplasmic tyrosine kinase c-Abl is an important effector of c-Src for PDGF- and serum-induced DNA synthesis. Inactivation of cytoplasmic c-Abl by the kinase- inacti...

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Detalhes bibliográficos
Main Authors: Furstoss, Olivia, Dorey, Karel, Simon, Valérie, Barilà, Daniela, Superti-Furga, Giulio, Roche, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125864/
https://ncbi.nlm.nih.gov/pubmed/11847100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.4.514
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