c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis

The mechanism by which the ubiquitously expressed Src family kinases regulate mitogenesis is not well understood. Here we report that cytoplasmic tyrosine kinase c-Abl is an important effector of c-Src for PDGF- and serum-induced DNA synthesis. Inactivation of cytoplasmic c-Abl by the kinase- inacti...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Furstoss, Olivia, Dorey, Karel, Simon, Valérie, Barilà, Daniela, Superti-Furga, Giulio, Roche, Serge
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2002
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125864/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11847100/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.4.514
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