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Caspase Cleavage Enhances the Apoptosis-Inducing Effects of BAD

The function of BAD, a proapoptotic member of the Bcl-2 family, is regulated primarily by rapid changes in phosphorylation that modulate its protein-protein interactions and subcellular localization. We show here that, during interleukin-3 (IL-3) deprivation-induced apoptosis of 32Dcl3 murine myeloi...

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Detalhes bibliográficos
Main Authors: Condorelli, Fabrizio, Salomoni, Paolo, Cotteret, Sophie, Cesi, Vincenzo, Srinivasula, Srinivasa M., Alnemri, Emad S., Calabretta, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86931/
https://ncbi.nlm.nih.gov/pubmed/11287608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.3025-3036.2001
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