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A Computational Approach to Analyze the Mechanism of Action of the Kinase Inhibitor Bafetinib

Prediction of drug action in human cells is a major challenge in biomedical research. Additionally, there is strong interest in finding new applications for approved drugs and identifying potential side effects. We present a computational strategy to predict mechanisms, risks and potential new domai...

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Autors principals: Burkard, Thomas R., Rix, Uwe, Breitwieser, Florian P., Superti-Furga, Giulio, Colinge, Jacques
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987840/
https://ncbi.nlm.nih.gov/pubmed/21124949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001001
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