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The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib
Dasatinib is a small-molecule kinase inhibitor used for the treatment of imatinib-resistant chronic myelogenous leukemia (CML). We have analyzed the kinases targeted by dasatinib by using an unbiased chemical proteomics approach to detect binding proteins directly from lysates of CML cells. Besides...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1940229/ https://ncbi.nlm.nih.gov/pubmed/17684099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702654104 |
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