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A Miniaturized Chemical Proteomic Approach for Target Profiling of Clinical Kinase Inhibitors in Tumor Biopsies

[Image: see text] While targeted therapy based on the idea of attenuating the activity of a preselected, therapeutically relevant protein has become one of the major trends in modern cancer therapy, no truly specific targeted drug has been developed and most clinical agents have displayed a degree o...

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Detalhes bibliográficos
Main Authors: Chamrád, Ivo, Rix, Uwe, Stukalov, Alexey, Gridling, Manuela, Parapatics, Katja, Müller, André C., Altiok, Soner, Colinge, Jacques, Superti-Furga, Giulio, Haura, Eric B., Bennett, Keiryn L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127982/
https://ncbi.nlm.nih.gov/pubmed/23901793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr400309p
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