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Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics

A growing number of gene mutations, which are recognized as cancer drivers, can be successfully targeted with drugs. The redundant and dynamic nature of oncogenic signaling networks and complex interactions between cancer cells and the microenvironment, however, can cause drug resistance. Whereas th...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Gridling, Manuela, Ficarro, Scott B., Breitwieser, Florian P., Song, Lanxi, Parapatics, Katja, Colinge, Jacques, Haura, Eric B., Marto, Jarrod A., Superti-Furga, Giulio, Bennett, Keiryn L., Rix, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4221415/
https://ncbi.nlm.nih.gov/pubmed/25189542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0152
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