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Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A

Sphingomyelin phosphodiesterase, acid-like 3A (SMPDL3A) is a member of a small family of proteins founded by the well characterized lysosomal enzyme, acid sphingomyelinase (ASMase). ASMase converts sphingomyelin into the signaling lipid, ceramide. It was recently discovered that, in contrast to ASMa...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gorelik, Alexei, Illes, Katalin, Superti-Furga, Giulio, Nagar, Bhushan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813564/
https://ncbi.nlm.nih.gov/pubmed/26792860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.711085
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