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Sphingomyelin Phosphodiesterase Acid-like 3A (SMPDL3A) Is a Novel Nucleotide Phosphodiesterase Regulated by Cholesterol in Human Macrophages

Cholesterol-loaded foam cell macrophages are prominent in atherosclerotic lesions and play complex roles in both inflammatory signaling and lipid metabolism, which are underpinned by large scale reprogramming of gene expression. We performed a microarray study of primary human macrophages that showe...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Traini, Mathew, Quinn, Carmel M., Sandoval, Cecilia, Johansson, Erik, Schroder, Kate, Kockx, Maaike, Meikle, Peter J., Jessup, Wendy, Kritharides, Leonard
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239637/
https://ncbi.nlm.nih.gov/pubmed/25288789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.612341
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