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Structural insights into the activation of MST3 by MO25
The MO25 scaffolding protein operates as critical regulator of a number of STE20 family protein kinases (e.g. MST and SPAK isoforms) as well as pseudokinases (e.g. STRAD isoforms that play a critical role in activating the LKB1 tumour suppressor). To better understand how MO25 interacts and stimulat...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Academic Press
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725419/ https://ncbi.nlm.nih.gov/pubmed/23296203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.12.113 |
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