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Crystal Structure of Human Aurora B in Complex with INCENP and VX-680
[Image: see text] We present the structure of the human Aurora B kinase domain in complex with the C-terminal Aurora-binding region of human INCENP and the Aurora kinase inhibitor VX-680. The structure unexpectedly reveals a dimeric arrangement of the Aurora B:INCENP complex, which was confirmed to...
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| 主要な著者: | , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2012
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3621106/ https://ncbi.nlm.nih.gov/pubmed/22920039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm3008954 |
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