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Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction

Fidelity of chromosome segregation is ensured by a tension-dependent error correction system that prevents stabilization of incorrect chromosome–microtubule attachments. Unattached or incorrectly attached chromosomes also activate the spindle assembly checkpoint, thus delaying mitotic exit until all...

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Hlavní autoři: Santaguida, Stefano, Vernieri, Claudio, Villa, Fabrizio, Ciliberto, Andrea, Musacchio, Andrea
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102279/
https://ncbi.nlm.nih.gov/pubmed/21407176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.70
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