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Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions

PDZ domains are protein–protein interaction modules that generally bind to the C termini of their target proteins. The C-terminal four amino acids of a prospective binding partner of a PDZ domain are typically the determinants of binding specificity. In an effort to determine the structures of a num...

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Detalhes bibliográficos
Main Authors: Elkins, Jonathan M., Papagrigoriou, Evangelos, Berridge, Georgina, Yang, Xiaowen, Phillips, Claire, Gileadi, Carina, Savitsky, Pavel, Doyle, Declan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203335/
https://ncbi.nlm.nih.gov/pubmed/17384233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062657507
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