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Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms
PDZ domains most commonly bind the C-terminus of their protein targets. Typically the C-terminal four residues of the protein target are considered as the binding motif, particularly the C-terminal residue (P0) and third-last residue (P-2) that form the major contacts with the PDZ domain's “bin...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867013/ https://ncbi.nlm.nih.gov/pubmed/20120020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.349 |
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