Bone Marrow Niche Trafficking of miR-126 Controls Self-Renewal of Leukemia Stem Cells in Chronic Myelogenous Leukemia

Por Zhang, Bin, Nguyen, Le Xuan Truong, Li, Ling, Zhao, Dandan, Kumar, Bijender, Wu, Herman, Lin, Allen, Pellicano, Francesca, Hopcroft, Lisa, Su, Yu-Lin, Copland, Mhairi, Holyoake, Tessa L., Kuo, Calvin J., Bhatia, Ravi, Snyder, David S., Ali, Haris, Stein, Anthony S., Brewer, Casey, Wang, Huafeng, McDonald, Tinisha, Swiderski, Piotr, Troadec, Estelle, Chen, Ching-Cheng, Dorrance, Adrienne, Pullarkat, Vinod, Yuan, Yate-Ching, Perrotti, Danilo, Carlesso, Nadia, Forman, Stephen J., Kortylewski, Marcin, Kuo, Ya-Huei, Marcucci, Guido
Publicado no Nat Med (2018)

Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

Por Dai, Xiangpeng, Gan, Wenjian, Li, Xiaoning, Wang, Shangqian, Zhang, Wei, Huang, Ling, Liu, Shengwu, Zhong, Qing, Guo, Jianping, Zhang, Jinfang, Chen, Ting, Shimizu, Kouhei, Beca, Francisco, Blattner, Mirjam, Vasudevan, Divya, Buckley, Dennis L., Qi, Jun, Buser, Lorenz, Liu, Pengda, Inuzuka, Hiroyuki, Beck, Andrew H., Wang, Liewei, Wild, Peter J., Garraway, Levi A., Rubin, Mark A., Barbieri, Christopher E., Wong, Kwok-Kin, Muthuswamy, Senthil K., Huang, Jiaoti, Chen, Yu, Bradner, James E., Wei, Wenyi
Publicado no Nat Med (2017)

A genome-wide RNA interference screen reveals an essential CREB3L2/ATF5/MCL1 survival pathway in malignant glioma with therapeutic implications

Por Sheng, Zhi, Li, Li, Zhu, Lihua J., Smith, Thomas W., Demers, Andrea, Ross, Alonzo H., Moser, Richard P., Green, Michael R.
Publicado em 2010

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

Por Li, Yun R, Li, Jin, Zhao, Sihai D, Bradfield, Jonathan P, Mentch, Frank D, Maggadottir, S Melkorka, Hou, Cuiping, Abrams, Debra J, Chang, Diana, Gao, Feng, Guo, Yiran, Wei, Zhi, Connolly, John J, Cardinale, Christopher J, Bakay, Marina, Glessner, Joseph T, Li, Dong, Kao, Charlly, Thomas, Kelly A, Qiu, Haijun, Chiavacci, Rosetta M, Kim, Cecilia E, Wang, Fengxiang, Snyder, James, Richie, Marylyn D, Flatø, Berit, Førre, Øystein, Denson, Lee A, Thompson, Susan D, Becker, Mara L, Guthery, Stephen L, Latiano, Anna, Perez, Elena, Resnick, Elena, Russell, Richard K, Wilson, David C, Silverberg, Mark S, Annese, Vito, Lie, Benedicte A, Punaro, Marilynn, Dubinsky, Marla C, Monos, Dimitri S, Strisciuglio, Caterina, Staiano, Annamaria, Miele, Erasmo, Kugathasan, Subra, Ellis, Justine A, Munro, Jane E, Sullivan, Kathleen E, Wise, Carol A, Chapel, Helen, Cunningham-Rundles, Charlotte, Grant, Struan F A, Orange, Jordan S, Sleiman, Patrick M A, Behrens, Edward M, Griffiths, Anne M, Satsangi, Jack, Finkel, Terri H, Keinan, Alon, Prak, Eline T Luning, Polychronakos, Constantin, Baldassano, Robert N, Li, Hongzhe, Keating, Brendan J, Hakonarson, Hakon
Publicado no Nat Med (2015)

Small-molecule targeting of brachyury transcription factor addiction in chordoma

Por Sharifnia, Tanaz, Wawer, Mathias J., Chen, Ting, Huang, Qing-Yuan, Weir, Barbara A., Sizemore, Ann, Lawlor, Matthew A., Goodale, Amy, Cowley, Glenn S., Vazquez, Francisca, Ott, Christopher J., Francis, Joshua M., Sassi, Slim, Cogswell, Patricia, Sheppard, Hadley E., Zhang, Tinghu, Gray, Nathanael S., Clarke, Paul A., Blagg, Julian, Workman, Paul, Sommer, Josh, Hornicek, Francis, Root, David E., Hahn, William C., Bradner, James E., Wong, Kwok K., Clemons, Paul A., Lin, Charles Y., Kotz, Joanne D., Schreiber, Stuart L.
Publicado no Nat Med (2019)

Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children.

Por Nielsen-Saines, Karin, Brasil, Patrícia, Kerin, Tara, Vasconcelos, Zilton, Gabaglia, Claudia Raja, Damasceno, Luana, Pone, Marcos, de Carvalho, Liege M. Abreu, Pone, Sheila M., Zin, Andrea A., Tsui, Irena, Salles, Tania Regina S., da Cunha, Denise Cotrim, Costa, Roozemerie Pereira, Malacarne, Jociele, Reis, Ana Beatriz, Hasue, Renata Hydee, Aizawa, Carolina Y.P., Genovesi, Fernanda F., Einspieler, Christa, Marschik, Peter B, Pereira, José Paulo, Gaw, Stephanie L., Adachi, Kristina, Cherry, James D., Xu, Zhiheng, Cheng, Genhong, Moreira, Maria Elisabeth
Publicado no Nat Med (2019)

Impact of Pre-adapted HIV Transmission

Por Carlson, Jonathan M., Du, Victor Y., Pfeifer, Nico, Bansal, Anju, Tan, Vincent Y.F., Power, Karen, Brumme, Chanson J., Kreimer, Anat, DeZiel, Charles E., Fusi, Nicolo, Schaefer, Malinda, Brockman, Mark A., Gilmour, Jill, Price, Matt A., Kilembe, William, Haubrich, Richard, John, Mina, Mallal, Simon, Shapiro, Roger, Frater, John, Harrigan, P. Richard, Ndung’u, Thumbi, Allen, Susan, Heckerman, David, Sidney, John, Allen, Todd M., Goulder, Philip J.R., Brumme, Zabrina L., Hunter, Eric, Goepfert, Paul A.
Publicado no Nat Med (2016)

A Highly Potent Long-Acting Small-Molecule HIV-1 Capsid Inhibitor with Efficacy in a Humanized Mouse Model

Por Yant, Stephen R., Mulato, Andrew, Hansen, Derek, Tse, Winston C., Niedziela-Majka, Anita, Zhang, Jennifer R., Stepan, George J., Jin, Debi, Wong, Melanie H., Perreira, Jill M., Singer, Eric, Papalia, Giuseppe A., Hu, Eric Y., Zheng, Jim, Lu, Bing, Schroeder, Scott D., Chou, Kevin, Ahmadyar, Shekeba, Liclican, Albert, Yu, Helen, Novikov, Nikolai, Paoli, Eric, Gonik, Daniel, Ram, Renee R., Hung, Magdeleine, McDougall, William M., Brass, Abraham L., Sundquist, Wesley I., Cihlar, Tomas, Link, John O.
Publicado no Nat Med (2019)

Mitochondrial iron chelation ameliorates cigarette-smoke induced bronchitis and emphysema in mice

Por Cloonan, Suzanne M., Glass, Kimberly, Laucho-Contreras, Maria E., Bhashyam, Abhiram R., Cervo, Morgan, Pabón, Maria A., Konrad, Csaba, Polverino, Francesca, Siempos, Ilias I., Perez, Elizabeth, Mizumura, Kenji, Ghosh, Manik C., Parameswaran, Harikrishnan, Williams, Niamh C., Rooney, Kristen T., Chen, Zhi-Hua, Goldklang, Monica P., Yuan, Guo-Cheng, Moore, Stephen C., Demeo, Dawn L., Rouault, Tracey A., D’Armiento, Jeanine M., Schon, Eric A., Manfredi, Giovanni, Quackenbush, John, Mahmood, Ashfaq, Silverman, Edwin K., Owen, Caroline A., Choi, Augustine M.K.
Publicado no Nat Med (2016)

Immunogenic neoantigens derived from gene fusions stimulate T cell responses

Por Yang, Wei, Lee, Ken-Wing, Srivastava, Raghvendra M., Kuo, Fengshen, Krishna, Chirag, Chowell, Diego, Makarov, Vladimir, Hoen, Douglas, Dalin, Martin G., Wexler, Leonard, Ghossein, Ronald, Katabi, Nora, Nadeem, Zaineb, Cohen, Marc A., Tian, S. Ken, Robine, Nicolas, Arora, Kanika, Geiger, Heather, Agius, Phaedra, Bouvier, Nancy, Huberman, Kety, Vanness, Katelynd, Havel, Jonathan J., Sims, Jennifer S., Samstein, Robert M., Mandal, Rajarsi, Tepe, Justin, Ganly, Ian, Ho, Alan L., Riaz, Nadeem, Wong, Richard J., Shukla, Neerav, Chan, Timothy A., Morris, Luc G.T.
Publicado no Nat Med (2019)

Inhibitory effect of chemical constituents from Artemisia scoparia Waldst. et Kit. on triglyceride accumulation in 3T3-L1 cells and nitric oxide production in RAW 264.7 cells

Por Yahagi, Tadahiro, Yakura, Naoyuki, Matsuzaki, Keiichi, Kitanaka, Susumu
Publicado em 2013

Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca(2+) channel complex

Por Brittain, Joel M., Duarte, Djane B., Wilson, Sarah M., Zhu, Weiguo, Ballard, Carrie, Johnson, Phillip L., Liu, Naikui, Xiong, Wenhui, Ripsch, Matthew S., Wang, Yuying, Fehrenbacher, Jill C., Fitz, Stephanie D., Khanna, May, Park, Chul-Kyu, Schmutzler, Brian S., Cheon, Bo Myung, Due, Michael R., Brustovetsky, Tatiana, Ashpole, Nicole M., Hudmon, Andy, Meroueh, Samy O., Hingtgen, Cynthia M., Brustovetsky, Nikolay, Ji, Ru-Rong, Hurley, Joyce H., Jin, Xiaoming, Shekhar, Anantha, Xu, Xiao-Ming, Oxford, Gerry S., Vasko, Michael R., White, Fletcher A., Khanna, Rajesh
Publicado em 2011

A Clonal Expression Biomarker Associates With Lung Cancer Mortality

Por Biswas, Dhruva, Birkbak, Nicolai J, Rosenthal, Rachel, Hiley, Crispin T., Lim, Emilia L., Papp, Krisztian, Boeing, Stefan, Krzystanek, Marcin, Djureinovic, Dijana, La Fleur, Linnea, Greco, Maria, Döme, Balázs, Fillinger, János, Brunnström, Hans, Wu, Yin, Moore, David A., Skrzypski, Marcin, Abbosh, Christopher, Litchfield, Kevin, Al Bakir, Maise, Watkins, Thomas BK, Veeriah, Selvaraju, Wilson, Gareth A., Jamal-Hanjani, Mariam, Moldvay, Judit, Botling, Johan, Chinnaiyan, Arul M., Micke, Patrick, Hackshaw, Allan, Bartek, Jiri, Csabai, Istvan, Szallasi, Zoltan, Herrero, Javier, McGranahan, Nicholas, Swanton, Charles
Publicado no Nat Med (2019)

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

Por Frodermann, Vanessa, Rohde, David, Courties, Gabriel, Severe, Nicolas, Schloss, Maximilian J., Amatullah, Hajera, McAlpine, Cameron S., Cremer, Sebastian, Hoyer, Friedrich F., Ji, Fei, van Koeverden, Ian D., Herisson, Fanny, Honold, Lisa, Masson, Gustavo Santos, Zhang, Shuang, Grune, Jana, Iwamoto, Yoshiko, Schmidt, Stephen P., Wojtkiewicz, Gregory R., Lee, I-Hsiu, Gustafsson, Karin, Pasterkamp, Gerard, de Jager, Saskia C.A., Sadreyev, Ruslan I., MacFadyen, Jean, Libby, Peter, Ridker, Paul, Scadden, David T., Naxerova, Kamila, Jeffrey, Kate L., Swirski, Filip K., Nahrendorf, Matthias
Publicado no Nat Med (2019)

Safety and Efficacy of Autologous CD34+ Hematopoietic Progenitor Cells Transduced with an Anti-Tat Ribozyme in a Multi-Center, Randomized, Placebo-Controlled, Phase II Gene Therapy...

Por Mitsuyasu, Ronald T, Merigan, Thomas C, Carr, Andrew, Zack, Jerome A, Winters, Mark A, Workman, Cassy, Bloch, Mark, Lalezari, Jacob, Becker, Stephen, Thornton, Lorna, Akil, Bisher, Khanlou, Homayoon, Finlayson, Robert, McFarlane, Robert, Smith, Don E, Garsia, Roger, Ma, David, Law, Matthew, Murray, John M., von Kalle, Christof, Ely, Julie A, Patino, Sharon M, Knop, Alison E, Wong, Philip, Todd, Alison V, Haughton, Margaret, Fuery, Caroline, Macpherson, Janet L, Symonds, Geoff P, Evans, Louise A, Pond, Susan M, Cooper, David A
Publicado em 2009

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

Por Yun, Seung Pil, Kam, Tae-In, Panicker, Nikhil, Kim, SangMin, Oh, Yumin, Park, Jong-Sung, Kwon, Seung-Hwan, Park, Yong Joo, Karuppagounder, Senthilkumar S., Park, Hyejin, Kim, Sangjune, Oh, Nayeon, Kim, Nayoung Alice, Lee, Saebom, Brahmachari, Saurav, Mao, Xiaobo, Lee, Jun Hee, Kumar, Manoj, An, Daniel, Kang, Sung-Ung, Lee, Yunjong, Lee, Kang Choon, Na, Dong Hee, Kim, Donghoon, Lee, Sang Hun, Roschke, Viktor V., Liddelow, Shane A., Mari, Zoltan, Barres, Ben. A., Dawson, Valina L., Lee, Seulki, Dawson, Ted M., Ko, Han Seok
Publicado no Nat Med (2018)

Genetic variants at CD28, PRDM1, and CD2/CD58 are associated with rheumatoid arthritis risk

Por Raychaudhuri, Soumya, Thomson, Brian P., Remmers, Elaine F., Eyre, Stephen, Hinks, Anne, Guiducci, Candace, Catanese, Joseph J., Xie, Gang, Stahl, Eli A., Chen, Robert, Alfredsson, Lars, Amos, Christopher I., Ardlie, Kristin G., Barton, Anne, Bowes, John, Burtt, Noel P., Chang, Monica, Coblyn, Jonathan, Costenbader, Karen H., Criswell, Lindsey A., Crusius, J. Bart A., Cui, Jing, De Jager, Phillip L., Ding, Bo, Emery, Paul, Flynn, Edward, Harrison, Pille, Hocking, Lynne J., Huizinga, Tom W. J., Kastner, Daniel L., Ke, Xiayi, Kurreeman, Fina A. S., Lee, Annette T., Liu, Xiangdong, Li, Yonghong, Martin, Paul, Morgan, Ann W., Padyukov, Leonid, Reid, David M., Seielstad, Mark, Seldin, Michael F., Shadick, Nancy A., Steer, Sophia, Tak, Paul P., Thomson, Wendy, van der Helm-van Mil, Annette H. M., van der Horst-Bruinsma, Irene E., Weinblatt, Michael E., Wilson, Anthony G., Wolbink, Gert Jan, Wordsworth, Paul, Altshuler, David, Karlson, Elizabeth W., Toes, Rene E. M., de Vries, Niek, Begovich, Ann B., Siminovitch, Katherine A., Worthington, Jane, Klareskog, Lars, Gregersen, Peter K., Daly, Mark J., Plenge, Robert M.
Publicado em 2009

Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

Por Joshi, Kroopa, de Massy, Marc Robert, Ismail, Mazlina, Reading, James L., Uddin, Imran, Woolston, Annemarie, Hatipoglu, Emine, Oakes, Theres, Rosenthal, Rachel, Peacock, Thomas, Ronel, Tahel, Noursadeghi, Mahdad, Turati, Virginia, Furness, Andrew J. S., Georgiou, Andrew, Wong, Yien Ning Sophia, Aissa, Assma Ben, Werner Sunderland, Mariana, Jamal-Hanjani, Mariam, Veeriah, Selvaraju, Birkbak, Nicolai J., Wilson, Gareth A., Hiley, Crispin T., Ghorani, Ehsan, Guerra-Assunção, José Afonso, Herrero, Javier, Enver, Tariq, Hadrup, Sine R., Hackshaw, Allan, Peggs, Karl S., McGranahan, Nicholas, Swanton, Charles, Quezada, Sergio A., Chain, Benny
Publicado no Nat Med (2019)

Large-scale Proteomic Analysis of Alzheimer’s Disease Brain and Cerebrospinal Fluid Reveals Early Changes in Energy Metabolism Associated with Microglia and Astrocyte Activation

Por Johnson, Erik C.B., Dammer, Eric B., Duong, Duc M., Ping, Lingyan, Zhou, Maotian, Yin, Luming, Higginbotham, Lenora A., Guajardo, Andrew, White, Bartholomew, Troncoso, Juan C., Thambisetty, Madhav, Montine, Thomas J., Lee, Edward B., Trojanowski, John Q., Beach, Thomas G., Reiman, Eric M., Haroutunian, Vahram, Wang, Minghui, Schadt, Eric, Zhang, Bin, Dickson, Dennis W., Ertekin-Taner, Nilüfer, Golde, Todd E., Petyuk, Vladislav A., De Jager, Philip L., Bennett, David A., Wingo, Thomas S., Rangaraju, Srikant, Hajjar, Ihab, Shulman, Joshua M., Lah, James J., Levey, Allan I., Seyfried, Nicholas T.
Publicado no Nat Med (2020)

The TLX1 oncogene drives aneuploidy in T-cell transformation

Por De Keersmaecker, Kim, Real, Pedro Jose, Gatta, Giusy Della, Palomero, Teresa, Sulis, Maria Luisa, Tosello, Valeria, Van Vlierberghe, Pieter, Barnes, Kelly, Castillo, Mireia, Sole, Xavier, Hadler, Michael, Lenz, Jack, Aplan, Peter D., Kelliher, Michelle, Kee, Barbara L., Pandolfi, Pier Paolo, Kappes, Dietmar, Gounari, Fotini, Petrie, Howard, Van der Meulen, Joni, Speleman, Frank, Paietta, Elisabeth, Racevskis, Janis, Wiernik, Peter H., Rowe, Jacob M., Soulier, Jean, Avran, David, Cavé, Hélène, Dastugue, Nicole, Raimondi, Susana, Meijerink, Jules P.P., Cordon-Cardo, Carlos, Califano, Andrea, Ferrando, Adolfo A.
Publicado em 2010