Negative regulation of DAB2IP by Akt and SCF(Fbw7) pathways

par Dai, Xiangping, North, Brian J., Inuzuka, Hiroyuki
Publié 2014

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

par Tseng Alan, Inuzuka Hiroyuki, Gao Daming, Wei Wenyi
Publié 2009-06-01

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

par Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Wei, Wenyi
Publié 2009

Novel Insights into the Molecular Mechanisms Governing Mdm2 Ubiquitination and Destruction

par Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Wei, Wenyi
Publié 2010

Roles of F-box proteins in cancer

par Wang, Zhiwei, Liu, Pengda, Inuzuka, Hiroyuki, Wei, Wenyi
Publié dans Nat Rev Cancer (2014)

Degradation of the Transcription Factor Twist, an Oncoprotein that Promotes Cancer Metastasis

par Zhong, Jiateng, Ogura, Kohei, Wang, Zhiwei, Inuzuka, Hiroyuki
Publié dans Discov Med (2013)

SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation

par Lau, Alan W, Liu, Pengda, Inuzuka, Hiroyuki, Gao, Daming
Publié 2014

Physiological Functions of FBW7 in Cancer and Metabolism

par Shimizu, Kouhei, Nihira, Naoe Taira, Inuzuka, Hiroyuki, Wei, Wenyi
Publié dans Cell Signal (2018)

Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors

par Clement, Emilie, Inuzuka, Hiroyuki, Nihira, Naoe T., Wei, Wenyi, Toker, Alex
Publié dans Sci Signal (2018)

Acetylation-dependent regulation of essential iPS-inducing factors: a regulatory crossroad for pluripotency and tumorigenesis

par Dai, Xiangpeng, Liu, Pengda, Lau, Alan W, Liu, Yueyong, Inuzuka, Hiroyuki
Publié dans Cancer Med (2014)

DEPTOR ubiquitination and destruction by SCF(β-TrCP)

par Wang, Zhiwei, Zhong, Jiateng, Gao, Daming, Inuzuka, Hiroyuki, Liu, Pengda, Wei, Wenyi
Publié 2012

Deficiency of Lipin2 Results in Enhanced NF-κB Signaling and Osteoclast Formation in RAW-D Murine Macrophages

par Watahiki, Asami, Hoshikawa, Seira, Chiba, Mitsuki, Egusa, Hiroshi, Fukumoto, Satoshi, Inuzuka, Hiroyuki
Publié dans Int J Mol Sci (2021)

Phosphorylation by Akt1 Promotes Skp2 Cytoplasmic Localization and Impairs APC/Cdh1-mediated Skp2 Destruction

par Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Chin, Rebecca Y., Toker, Alex, Wei, Wenyi
Publié 2009

Mcl-1 Ubiquitination and Destruction

par Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Liu, Pengda, Lau, Alan W., Wei, Wenyi
Publié 2011

Smurf1 regulation of DAB2IP controls cell proliferation and migration

par Li, Xiaoning, Dai, Xiangpeng, Wan, Lixin, Inuzuka, Hiroyuki, Sun, Liankun, North, Brian J.
Publié dans Oncotarget (2016)

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction

par Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Fukushima, Hidefumi, Wan, Lixin, Liu, Pengda, Wei, Wenyi
Publié 2012

SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway

par Liu, Jia, Wan, Lixin, Liu, Pengda, Inuzuka, Hiroyuki, Liu, Jiankang, Wang, Zhiwei, Wei, Wenyi
Publié 2014

SGK3 mediates INPP4B-dependent PI 3-Kinase signaling in breast cancer

par Gasser, Jessica A., Inuzuka, Hiroyuki, Lau, Alan W., Wei, Wenyi, Beroukhim, Rameen, Toker, Alex
Publié dans Mol Cell (2014)

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

par Takada, Mamoru, Zhuang, Ming, Inuzuka, Hiroyuki, Zhang, Jing, Zurlo, Giada, Zhang, Jinfang, Zhang, Qing
Publié dans Oncotarget (2016)

Tumor Suppressor Functions of FBW7 in Cancer Development and Progression

par Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Wan, Lixin, Fukushima, Hidefumi, Sarkar, Fazlul H., Wei, Wenyi
Publié 2012