Negative regulation of DAB2IP by Akt and SCF(Fbw7) pathways

by Dai, Xiangping, North, Brian J., Inuzuka, Hiroyuki
Published 2014

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

by Tseng Alan, Inuzuka Hiroyuki, Gao Daming, Wei Wenyi
Published 2009-06-01

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

by Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Wei, Wenyi
Published 2009

Novel Insights into the Molecular Mechanisms Governing Mdm2 Ubiquitination and Destruction

by Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Wei, Wenyi
Published 2010

Roles of F-box proteins in cancer

by Wang, Zhiwei, Liu, Pengda, Inuzuka, Hiroyuki, Wei, Wenyi
Published in Nat Rev Cancer (2014)

Degradation of the Transcription Factor Twist, an Oncoprotein that Promotes Cancer Metastasis

by Zhong, Jiateng, Ogura, Kohei, Wang, Zhiwei, Inuzuka, Hiroyuki
Published in Discov Med (2013)

SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation

by Lau, Alan W, Liu, Pengda, Inuzuka, Hiroyuki, Gao, Daming
Published 2014

Physiological Functions of FBW7 in Cancer and Metabolism

by Shimizu, Kouhei, Nihira, Naoe Taira, Inuzuka, Hiroyuki, Wei, Wenyi
Published in Cell Signal (2018)

Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors

by Clement, Emilie, Inuzuka, Hiroyuki, Nihira, Naoe T., Wei, Wenyi, Toker, Alex
Published in Sci Signal (2018)

Acetylation-dependent regulation of essential iPS-inducing factors: a regulatory crossroad for pluripotency and tumorigenesis

by Dai, Xiangpeng, Liu, Pengda, Lau, Alan W, Liu, Yueyong, Inuzuka, Hiroyuki
Published in Cancer Med (2014)

DEPTOR ubiquitination and destruction by SCF(β-TrCP)

by Wang, Zhiwei, Zhong, Jiateng, Gao, Daming, Inuzuka, Hiroyuki, Liu, Pengda, Wei, Wenyi
Published 2012

Deficiency of Lipin2 Results in Enhanced NF-κB Signaling and Osteoclast Formation in RAW-D Murine Macrophages

by Watahiki, Asami, Hoshikawa, Seira, Chiba, Mitsuki, Egusa, Hiroshi, Fukumoto, Satoshi, Inuzuka, Hiroyuki
Published in Int J Mol Sci (2021)

Phosphorylation by Akt1 Promotes Skp2 Cytoplasmic Localization and Impairs APC/Cdh1-mediated Skp2 Destruction

by Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Chin, Rebecca Y., Toker, Alex, Wei, Wenyi
Published 2009

Mcl-1 Ubiquitination and Destruction

by Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Liu, Pengda, Lau, Alan W., Wei, Wenyi
Published 2011

Smurf1 regulation of DAB2IP controls cell proliferation and migration

by Li, Xiaoning, Dai, Xiangpeng, Wan, Lixin, Inuzuka, Hiroyuki, Sun, Liankun, North, Brian J.
Published in Oncotarget (2016)

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction

by Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Fukushima, Hidefumi, Wan, Lixin, Liu, Pengda, Wei, Wenyi
Published 2012

SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway

by Liu, Jia, Wan, Lixin, Liu, Pengda, Inuzuka, Hiroyuki, Liu, Jiankang, Wang, Zhiwei, Wei, Wenyi
Published 2014

SGK3 mediates INPP4B-dependent PI 3-Kinase signaling in breast cancer

by Gasser, Jessica A., Inuzuka, Hiroyuki, Lau, Alan W., Wei, Wenyi, Beroukhim, Rameen, Toker, Alex
Published in Mol Cell (2014)

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

by Takada, Mamoru, Zhuang, Ming, Inuzuka, Hiroyuki, Zhang, Jing, Zurlo, Giada, Zhang, Jinfang, Zhang, Qing
Published in Oncotarget (2016)

Tumor Suppressor Functions of FBW7 in Cancer Development and Progression

by Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Wan, Lixin, Fukushima, Hidefumi, Sarkar, Fazlul H., Wei, Wenyi
Published 2012