Negative regulation of DAB2IP by Akt and SCF(Fbw7) pathways

por Dai, Xiangping, North, Brian J., Inuzuka, Hiroyuki
Publicado 2014

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

por Tseng Alan, Inuzuka Hiroyuki, Gao Daming, Wei Wenyi
Publicado 2009-06-01

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

por Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Wei, Wenyi
Publicado 2009

Novel Insights into the Molecular Mechanisms Governing Mdm2 Ubiquitination and Destruction

por Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Wei, Wenyi
Publicado 2010

Roles of F-box proteins in cancer

por Wang, Zhiwei, Liu, Pengda, Inuzuka, Hiroyuki, Wei, Wenyi
Publicado en Nat Rev Cancer (2014)

Degradation of the Transcription Factor Twist, an Oncoprotein that Promotes Cancer Metastasis

por Zhong, Jiateng, Ogura, Kohei, Wang, Zhiwei, Inuzuka, Hiroyuki
Publicado en Discov Med (2013)

SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation

por Lau, Alan W, Liu, Pengda, Inuzuka, Hiroyuki, Gao, Daming
Publicado 2014

Physiological Functions of FBW7 in Cancer and Metabolism

por Shimizu, Kouhei, Nihira, Naoe Taira, Inuzuka, Hiroyuki, Wei, Wenyi
Publicado en Cell Signal (2018)

Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors

por Clement, Emilie, Inuzuka, Hiroyuki, Nihira, Naoe T., Wei, Wenyi, Toker, Alex
Publicado en Sci Signal (2018)

Acetylation-dependent regulation of essential iPS-inducing factors: a regulatory crossroad for pluripotency and tumorigenesis

por Dai, Xiangpeng, Liu, Pengda, Lau, Alan W, Liu, Yueyong, Inuzuka, Hiroyuki
Publicado en Cancer Med (2014)

DEPTOR ubiquitination and destruction by SCF(β-TrCP)

por Wang, Zhiwei, Zhong, Jiateng, Gao, Daming, Inuzuka, Hiroyuki, Liu, Pengda, Wei, Wenyi
Publicado 2012

Deficiency of Lipin2 Results in Enhanced NF-κB Signaling and Osteoclast Formation in RAW-D Murine Macrophages

por Watahiki, Asami, Hoshikawa, Seira, Chiba, Mitsuki, Egusa, Hiroshi, Fukumoto, Satoshi, Inuzuka, Hiroyuki
Publicado en Int J Mol Sci (2021)

Phosphorylation by Akt1 Promotes Skp2 Cytoplasmic Localization and Impairs APC/Cdh1-mediated Skp2 Destruction

por Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Chin, Rebecca Y., Toker, Alex, Wei, Wenyi
Publicado 2009

Mcl-1 Ubiquitination and Destruction

por Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Liu, Pengda, Lau, Alan W., Wei, Wenyi
Publicado 2011

Smurf1 regulation of DAB2IP controls cell proliferation and migration

por Li, Xiaoning, Dai, Xiangpeng, Wan, Lixin, Inuzuka, Hiroyuki, Sun, Liankun, North, Brian J.
Publicado en Oncotarget (2016)

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction

por Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Fukushima, Hidefumi, Wan, Lixin, Liu, Pengda, Wei, Wenyi
Publicado 2012

SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway

por Liu, Jia, Wan, Lixin, Liu, Pengda, Inuzuka, Hiroyuki, Liu, Jiankang, Wang, Zhiwei, Wei, Wenyi
Publicado 2014

SGK3 mediates INPP4B-dependent PI 3-Kinase signaling in breast cancer

por Gasser, Jessica A., Inuzuka, Hiroyuki, Lau, Alan W., Wei, Wenyi, Beroukhim, Rameen, Toker, Alex
Publicado en Mol Cell (2014)

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

por Takada, Mamoru, Zhuang, Ming, Inuzuka, Hiroyuki, Zhang, Jing, Zurlo, Giada, Zhang, Jinfang, Zhang, Qing
Publicado en Oncotarget (2016)

Tumor Suppressor Functions of FBW7 in Cancer Development and Progression

por Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Wan, Lixin, Fukushima, Hidefumi, Sarkar, Fazlul H., Wei, Wenyi
Publicado 2012