Negative regulation of DAB2IP by Akt and SCF(Fbw7) pathways

door Dai, Xiangping, North, Brian J., Inuzuka, Hiroyuki
Gepubliceerd in 2014

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

door Tseng Alan, Inuzuka Hiroyuki, Gao Daming, Wei Wenyi
Gepubliceerd in 2009-06-01

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

door Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Wei, Wenyi
Gepubliceerd in 2009

Novel Insights into the Molecular Mechanisms Governing Mdm2 Ubiquitination and Destruction

door Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Wei, Wenyi
Gepubliceerd in 2010

Roles of F-box proteins in cancer

door Wang, Zhiwei, Liu, Pengda, Inuzuka, Hiroyuki, Wei, Wenyi
Gepubliceerd in Nat Rev Cancer (2014)

Degradation of the Transcription Factor Twist, an Oncoprotein that Promotes Cancer Metastasis

door Zhong, Jiateng, Ogura, Kohei, Wang, Zhiwei, Inuzuka, Hiroyuki
Gepubliceerd in Discov Med (2013)

SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation

door Lau, Alan W, Liu, Pengda, Inuzuka, Hiroyuki, Gao, Daming
Gepubliceerd in 2014

Physiological Functions of FBW7 in Cancer and Metabolism

door Shimizu, Kouhei, Nihira, Naoe Taira, Inuzuka, Hiroyuki, Wei, Wenyi
Gepubliceerd in Cell Signal (2018)

Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors

door Clement, Emilie, Inuzuka, Hiroyuki, Nihira, Naoe T., Wei, Wenyi, Toker, Alex
Gepubliceerd in Sci Signal (2018)

Acetylation-dependent regulation of essential iPS-inducing factors: a regulatory crossroad for pluripotency and tumorigenesis

door Dai, Xiangpeng, Liu, Pengda, Lau, Alan W, Liu, Yueyong, Inuzuka, Hiroyuki
Gepubliceerd in Cancer Med (2014)

DEPTOR ubiquitination and destruction by SCF(β-TrCP)

door Wang, Zhiwei, Zhong, Jiateng, Gao, Daming, Inuzuka, Hiroyuki, Liu, Pengda, Wei, Wenyi
Gepubliceerd in 2012

Deficiency of Lipin2 Results in Enhanced NF-κB Signaling and Osteoclast Formation in RAW-D Murine Macrophages

door Watahiki, Asami, Hoshikawa, Seira, Chiba, Mitsuki, Egusa, Hiroshi, Fukumoto, Satoshi, Inuzuka, Hiroyuki
Gepubliceerd in Int J Mol Sci (2021)

Phosphorylation by Akt1 Promotes Skp2 Cytoplasmic Localization and Impairs APC/Cdh1-mediated Skp2 Destruction

door Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Chin, Rebecca Y., Toker, Alex, Wei, Wenyi
Gepubliceerd in 2009

Mcl-1 Ubiquitination and Destruction

door Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Liu, Pengda, Lau, Alan W., Wei, Wenyi
Gepubliceerd in 2011

Smurf1 regulation of DAB2IP controls cell proliferation and migration

door Li, Xiaoning, Dai, Xiangpeng, Wan, Lixin, Inuzuka, Hiroyuki, Sun, Liankun, North, Brian J.
Gepubliceerd in Oncotarget (2016)

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction

door Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Fukushima, Hidefumi, Wan, Lixin, Liu, Pengda, Wei, Wenyi
Gepubliceerd in 2012

SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway

door Liu, Jia, Wan, Lixin, Liu, Pengda, Inuzuka, Hiroyuki, Liu, Jiankang, Wang, Zhiwei, Wei, Wenyi
Gepubliceerd in 2014

SGK3 mediates INPP4B-dependent PI 3-Kinase signaling in breast cancer

door Gasser, Jessica A., Inuzuka, Hiroyuki, Lau, Alan W., Wei, Wenyi, Beroukhim, Rameen, Toker, Alex
Gepubliceerd in Mol Cell (2014)

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

door Takada, Mamoru, Zhuang, Ming, Inuzuka, Hiroyuki, Zhang, Jing, Zurlo, Giada, Zhang, Jinfang, Zhang, Qing
Gepubliceerd in Oncotarget (2016)

Tumor Suppressor Functions of FBW7 in Cancer Development and Progression

door Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Wan, Lixin, Fukushima, Hidefumi, Sarkar, Fazlul H., Wei, Wenyi
Gepubliceerd in 2012