Negative regulation of DAB2IP by Akt and SCF(Fbw7) pathways

af Dai, Xiangping, North, Brian J., Inuzuka, Hiroyuki
Udgivet 2014

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

af Tseng Alan, Inuzuka Hiroyuki, Gao Daming, Wei Wenyi
Udgivet 2009-06-01

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

af Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Wei, Wenyi
Udgivet 2009

Novel Insights into the Molecular Mechanisms Governing Mdm2 Ubiquitination and Destruction

af Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Wei, Wenyi
Udgivet 2010

Roles of F-box proteins in cancer

af Wang, Zhiwei, Liu, Pengda, Inuzuka, Hiroyuki, Wei, Wenyi
Udgivet i Nat Rev Cancer (2014)

Degradation of the Transcription Factor Twist, an Oncoprotein that Promotes Cancer Metastasis

af Zhong, Jiateng, Ogura, Kohei, Wang, Zhiwei, Inuzuka, Hiroyuki
Udgivet i Discov Med (2013)

SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation

af Lau, Alan W, Liu, Pengda, Inuzuka, Hiroyuki, Gao, Daming
Udgivet 2014

Physiological Functions of FBW7 in Cancer and Metabolism

af Shimizu, Kouhei, Nihira, Naoe Taira, Inuzuka, Hiroyuki, Wei, Wenyi
Udgivet i Cell Signal (2018)

Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors

af Clement, Emilie, Inuzuka, Hiroyuki, Nihira, Naoe T., Wei, Wenyi, Toker, Alex
Udgivet i Sci Signal (2018)

Acetylation-dependent regulation of essential iPS-inducing factors: a regulatory crossroad for pluripotency and tumorigenesis

af Dai, Xiangpeng, Liu, Pengda, Lau, Alan W, Liu, Yueyong, Inuzuka, Hiroyuki
Udgivet i Cancer Med (2014)

DEPTOR ubiquitination and destruction by SCF(β-TrCP)

af Wang, Zhiwei, Zhong, Jiateng, Gao, Daming, Inuzuka, Hiroyuki, Liu, Pengda, Wei, Wenyi
Udgivet 2012

Deficiency of Lipin2 Results in Enhanced NF-κB Signaling and Osteoclast Formation in RAW-D Murine Macrophages

af Watahiki, Asami, Hoshikawa, Seira, Chiba, Mitsuki, Egusa, Hiroshi, Fukumoto, Satoshi, Inuzuka, Hiroyuki
Udgivet i Int J Mol Sci (2021)

Phosphorylation by Akt1 Promotes Skp2 Cytoplasmic Localization and Impairs APC/Cdh1-mediated Skp2 Destruction

af Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Chin, Rebecca Y., Toker, Alex, Wei, Wenyi
Udgivet 2009

Mcl-1 Ubiquitination and Destruction

af Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Liu, Pengda, Lau, Alan W., Wei, Wenyi
Udgivet 2011

Smurf1 regulation of DAB2IP controls cell proliferation and migration

af Li, Xiaoning, Dai, Xiangpeng, Wan, Lixin, Inuzuka, Hiroyuki, Sun, Liankun, North, Brian J.
Udgivet i Oncotarget (2016)

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction

af Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Fukushima, Hidefumi, Wan, Lixin, Liu, Pengda, Wei, Wenyi
Udgivet 2012

SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway

af Liu, Jia, Wan, Lixin, Liu, Pengda, Inuzuka, Hiroyuki, Liu, Jiankang, Wang, Zhiwei, Wei, Wenyi
Udgivet 2014

SGK3 mediates INPP4B-dependent PI 3-Kinase signaling in breast cancer

af Gasser, Jessica A., Inuzuka, Hiroyuki, Lau, Alan W., Wei, Wenyi, Beroukhim, Rameen, Toker, Alex
Udgivet i Mol Cell (2014)

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

af Takada, Mamoru, Zhuang, Ming, Inuzuka, Hiroyuki, Zhang, Jing, Zurlo, Giada, Zhang, Jinfang, Zhang, Qing
Udgivet i Oncotarget (2016)

Tumor Suppressor Functions of FBW7 in Cancer Development and Progression

af Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Wan, Lixin, Fukushima, Hidefumi, Sarkar, Fazlul H., Wei, Wenyi
Udgivet 2012