Negative regulation of DAB2IP by Akt and SCF(Fbw7) pathways

по Dai, Xiangping, North, Brian J., Inuzuka, Hiroyuki
Опубликовано 2014

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

по Tseng Alan, Inuzuka Hiroyuki, Gao Daming, Wei Wenyi
Опубликовано 2009-06-01

Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1

по Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Wei, Wenyi
Опубликовано 2009

Novel Insights into the Molecular Mechanisms Governing Mdm2 Ubiquitination and Destruction

по Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Wei, Wenyi
Опубликовано 2010

Roles of F-box proteins in cancer

по Wang, Zhiwei, Liu, Pengda, Inuzuka, Hiroyuki, Wei, Wenyi
Опубликовано в: Nat Rev Cancer (2014)

Degradation of the Transcription Factor Twist, an Oncoprotein that Promotes Cancer Metastasis

по Zhong, Jiateng, Ogura, Kohei, Wang, Zhiwei, Inuzuka, Hiroyuki
Опубликовано в: Discov Med (2013)

SIRT1 phosphorylation by AMP-activated protein kinase regulates p53 acetylation

по Lau, Alan W, Liu, Pengda, Inuzuka, Hiroyuki, Gao, Daming
Опубликовано 2014

Physiological Functions of FBW7 in Cancer and Metabolism

по Shimizu, Kouhei, Nihira, Naoe Taira, Inuzuka, Hiroyuki, Wei, Wenyi
Опубликовано в: Cell Signal (2018)

Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors

по Clement, Emilie, Inuzuka, Hiroyuki, Nihira, Naoe T., Wei, Wenyi, Toker, Alex
Опубликовано в: Sci Signal (2018)

Acetylation-dependent regulation of essential iPS-inducing factors: a regulatory crossroad for pluripotency and tumorigenesis

по Dai, Xiangpeng, Liu, Pengda, Lau, Alan W, Liu, Yueyong, Inuzuka, Hiroyuki
Опубликовано в: Cancer Med (2014)

DEPTOR ubiquitination and destruction by SCF(β-TrCP)

по Wang, Zhiwei, Zhong, Jiateng, Gao, Daming, Inuzuka, Hiroyuki, Liu, Pengda, Wei, Wenyi
Опубликовано 2012

Deficiency of Lipin2 Results in Enhanced NF-κB Signaling and Osteoclast Formation in RAW-D Murine Macrophages

по Watahiki, Asami, Hoshikawa, Seira, Chiba, Mitsuki, Egusa, Hiroshi, Fukumoto, Satoshi, Inuzuka, Hiroyuki
Опубликовано в: Int J Mol Sci (2021)

Phosphorylation by Akt1 Promotes Skp2 Cytoplasmic Localization and Impairs APC/Cdh1-mediated Skp2 Destruction

по Gao, Daming, Inuzuka, Hiroyuki, Tseng, Alan, Chin, Rebecca Y., Toker, Alex, Wei, Wenyi
Опубликовано 2009

Mcl-1 Ubiquitination and Destruction

по Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Liu, Pengda, Lau, Alan W., Wei, Wenyi
Опубликовано 2011

Smurf1 regulation of DAB2IP controls cell proliferation and migration

по Li, Xiaoning, Dai, Xiangpeng, Wan, Lixin, Inuzuka, Hiroyuki, Sun, Liankun, North, Brian J.
Опубликовано в: Oncotarget (2016)

DNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destruction

по Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Fukushima, Hidefumi, Wan, Lixin, Liu, Pengda, Wei, Wenyi
Опубликовано 2012

SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway

по Liu, Jia, Wan, Lixin, Liu, Pengda, Inuzuka, Hiroyuki, Liu, Jiankang, Wang, Zhiwei, Wei, Wenyi
Опубликовано 2014

SGK3 mediates INPP4B-dependent PI 3-Kinase signaling in breast cancer

по Gasser, Jessica A., Inuzuka, Hiroyuki, Lau, Alan W., Wei, Wenyi, Beroukhim, Rameen, Toker, Alex
Опубликовано в: Mol Cell (2014)

EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor

по Takada, Mamoru, Zhuang, Ming, Inuzuka, Hiroyuki, Zhang, Jing, Zurlo, Giada, Zhang, Jinfang, Zhang, Qing
Опубликовано в: Oncotarget (2016)

Tumor Suppressor Functions of FBW7 in Cancer Development and Progression

по Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Wan, Lixin, Fukushima, Hidefumi, Sarkar, Fazlul H., Wei, Wenyi
Опубликовано 2012