DEPTOR ubiquitination and destruction by SCF(β-TrCP)

β-Transducin repeats-containing protein (β-TrCP) is the substrate recognition subunit of the SCF (SKP1, CUL1, and F-box protein)-type E3 ubiquitin ligase complex. SCF(β-TrCP) ubiquitinates specifically phosphorylated substrates to promote their subsequent destruction by the 26S proteasome and plays...

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Autors principals: Wang, Zhiwei, Zhong, Jiateng, Gao, Daming, Inuzuka, Hiroyuki, Liu, Pengda, Wei, Wenyi
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431131/
https://ncbi.nlm.nih.gov/pubmed/22454292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00105.2012
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