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Pseudosubstrate regulation of the SCF(β-TrCP) ubiquitin ligase by hnRNP-U
β-TrCP/E3RS (E3RS) is the F-box protein that functions as the receptor subunit of the SCF(β-TrCP) ubiquitin ligase (E3). Surprisingly, although its two recognized substrates, IκBα and β-catenin, are present in the cytoplasm, we have found that E3RS is located predominantly in the nucleus. Here we re...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC155337/ https://ncbi.nlm.nih.gov/pubmed/11850407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.218702 |
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