Pseudosubstrate regulation of the SCF(β-TrCP) ubiquitin ligase by hnRNP-U

β-TrCP/E3RS (E3RS) is the F-box protein that functions as the receptor subunit of the SCF(β-TrCP) ubiquitin ligase (E3). Surprisingly, although its two recognized substrates, IκBα and β-catenin, are present in the cytoplasm, we have found that E3RS is located predominantly in the nucleus. Here we re...

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הוצא לאור ב:	Genes Dev
Principais autores:	Davis, Matti, Hatzubai, Ada, Andersen, Jens S., Ben-Shushan, Etti, Fisher, Gregory Zvi, Yaron, Avraham, Bauskin, Asne, Mercurio, Frank, Mann, Matthias, Ben-Neriah, Yinon
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Cold Spring Harbor Laboratory Press 2002
נושאים:	Research Paper
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155337/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11850407/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.218702
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