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Tumor Suppressor Functions of FBW7 in Cancer Development and Progression
FBW7 (F-box and WD repeat domain-containing 7) has been characterized as an onco-suppressor protein in human cancers. Recent studies have also shown that FBW7 exerts its anti-tumor function primarily by promoting the degradation of various oncoproteins, through which FBW7 regulates cellular prolifer...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372850/ https://ncbi.nlm.nih.gov/pubmed/22673505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.03.017 |
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