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Tumor Suppressor Functions of FBW7 in Cancer Development and Progression

FBW7 (F-box and WD repeat domain-containing 7) has been characterized as an onco-suppressor protein in human cancers. Recent studies have also shown that FBW7 exerts its anti-tumor function primarily by promoting the degradation of various oncoproteins, through which FBW7 regulates cellular prolifer...

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Hlavní autoři: Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Wan, Lixin, Fukushima, Hidefumi, Sarkar, Fazlul H., Wei, Wenyi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372850/
https://ncbi.nlm.nih.gov/pubmed/22673505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.03.017
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