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Novel Insights into the Molecular Mechanisms Governing Mdm2 Ubiquitination and Destruction

The Mdm2/p53 pathway is compromised in more than 50% of all human cancers, therefore it is an intensive area of research to understand the upstream regulatory pathways governing Mdm2/p53 activity. Mdm2 is frequently overexpressed in human cancers while the molecular mechanisms underlying the timely...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Wei, Wenyi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248122/
https://ncbi.nlm.nih.gov/pubmed/21317463
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!