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Mcl-1 Ubiquitination and Destruction
Loss of the Fbw7 tumor suppressor is common in diverse human cancer types, including T-Cell Acute Lymphoblastic Leukemia (T-ALL), although the mechanistic basis of its anti-oncogenic activity remains largely unclear. We recently reported that SCF(Fbw7) regulates cellular apoptosis by controlling the...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Impact Journals LLC
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3260810/ https://ncbi.nlm.nih.gov/pubmed/21608150 |
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