Mcl-1 Ubiquitination and Destruction

Loss of the Fbw7 tumor suppressor is common in diverse human cancer types, including T-Cell Acute Lymphoblastic Leukemia (T-ALL), although the mechanistic basis of its anti-oncogenic activity remains largely unclear. We recently reported that SCF(Fbw7) regulates cellular apoptosis by controlling the...

Full description

Saved in:
Bibliographic Details
Main Authors: Inuzuka, Hiroyuki, Fukushima, Hidefumi, Shaik, Shavali, Liu, Pengda, Lau, Alan W., Wei, Wenyi
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2011
Subjects:
Research Perspectives
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260810/
https://ncbi.nlm.nih.gov/pubmed/21608150
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items