SCF(Fbw7) Regulates Cellular Apoptosis By Targeting Mcl-1 for Ubiquitination and Destruction

The effective use of targeted therapy is highly dependent upon the identification of responder patient populations. Loss of the Fbw7 tumor suppressor is frequently found in various types of human cancers including breast cancer, colon cancer 1 and T-cell acute lymphoblastic leukemia (T-ALL)2. In lin...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Inuzuka, Hiroyuki, Shaik, Shavali, Onoyama, Ichiro, Gao, Daming, Tseng, Alan, Maser, Richard S., Zhai, Bo, Wan, Lixin, Gutierrez, Alejandro, Lau, Alan W., Xiao, Yonghong, Christie, Amanda L., Aster, Jon, Settleman, Jeffrey, Gygi, Steven P., Kung, Andrew L., Look, Thomas, Nakayama, Keiichi I., DePinho, Ronald A., Wei, Wenyi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076007/
https://ncbi.nlm.nih.gov/pubmed/21368833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09732
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares