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SCF(Fbw7) Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction
The NFκB/Rel family of proteins play critical roles in a variety of cellular processes. Thus, their physiological activation is tightly controlled. Recently, the NFκB2/p100 precursor has been characterized as the fourth IκB type of suppressor for NFκB. However, the molecular mechanism(s) underlying...
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| Asıl Yazarlar: | , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375724/ https://ncbi.nlm.nih.gov/pubmed/22708077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.04.002 |
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