SCF(β-TRCP) suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2

The incidence of human papillary thyroid cancer (PTC) is increasing and an aggressive subtype of this disease is resistant to treatment with vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor. VEGFR2 promotes angiogenesis by triggering endothelial cell proliferation and migration. Howe...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shaik, Shavali, Nucera, Carmelo, Inuzuka, Hiroyuki, Gao, Daming, Garnaas, Maija, Frechette, Gregory, Harris, Lauren, Wan, Lixin, Fukushima, Hidefumi, Husain, Amjad, Nose, Vania, Fadda, Guido, Sadow, Peter M., Goessling, Wolfram, North, Trista, Lawler, Jack, Wei, Wenyi
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405505/
https://ncbi.nlm.nih.gov/pubmed/22711876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112446
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados