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Physiological Functions of FBW7 in Cancer and Metabolism
FBW7 is one of the most well characterized F-box proteins that serve as substrate recognition subunits of SCF (Skp1-Cullin 1-F-box proteins) E3 ubiquitin ligase complexes. SCF(FBW7) plays key roles in regulating cell cycle progression, differentiation, and stem cell maintenance largely through targe...
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| Udgivet i: | Cell Signal |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5882551/ https://ncbi.nlm.nih.gov/pubmed/29474981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.02.009 |
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