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Roles of F-box proteins in cancer
F-box proteins, which are the substrate-recognition subunits of SKP1–cullin 1–F-box protein (SCF) E3 ligase complexes, have pivotal roles in multiple cellular processes through ubiquitylation and subsequent degradation of target proteins. Dysregulation of F-box protein-mediated proteolysis leads to...
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| Publicado no: | Nat Rev Cancer |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4306233/ https://ncbi.nlm.nih.gov/pubmed/24658274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3700 |
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